Could I have a statement, please? <a href="http://www.sandbox.cardinalsystems.com.ar/stmap_eafa0.html?zanaflex.viagra.metronidazole.sleepwell">naturallygoodhealth.com</a>  Irregular bedtimes appeared to disrupt the circadian rhythm - the body's internal clock - which led to sleep deprivation. This affected development of the brain, specifically undermining maturation and the ability to regulate certain types of behaviour.